XRCC2 promotes cancer progression by regulating p53/p21 signaling pathway in hepatocellular carcinoma
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چکیده
منابع مشابه
CDCA7L promotes hepatocellular carcinoma progression by regulating the cell cycle.
The cell division cycle-associated 7-like protein (CDCA7L) is a recently-identified target gene of c-Myc which can also interact with c-Myc. It is known to be upregulated in many tumors, however, its role in tumor progression remains unclear. We investigated the role of CDCA7L expression in hepatocellular carcinoma (HCC). We confirmed that CDCA7L is strongly upregulated in human HCC, and demons...
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Objective(s): Hepatocellular carcinoma (HCC) is one of the leading fatal neoplasms and the most common primary liver malignancy worldwide. Peptide hormone ANGPTL8 (betatrophin) may act as an important regulator in HCC development through the Wnt/β-catenin pathway. We aimed to evaluate the effects of recombinant ANGPTL8 on Wnt/β-catenin signaling in human liver carcinom...
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ژورنال
عنوان ژورنال: HPB
سال: 2019
ISSN: 1365-182X
DOI: 10.1016/j.hpb.2019.10.1974